Shaoxi Cai Selected Research

Monoclonal Antibodies

11/2023	IL-17A promotes tumorigenesis and upregulates PD-L1 expression in non-small cell lung cancer.
3/2022	Anti-PD-L1 antibody alleviates pulmonary fibrosis by inducing autophagy via inhibition of the PI3K/Akt/mTOR pathway.
1/2021	Extracellular HSP90α Interacts With ER Stress to Promote Fibroblasts Activation Through PI3K/AKT Pathway in Pulmonary Fibrosis.
12/2017	Blockade of extracellular heat shock protein 90α by 1G6-D7 attenuates pulmonary fibrosis through inhibiting ERK signaling.
1/2016	Bevacizumab reduced auto-phosphorylation of VEGFR2 to protect HDM-induced asthma mice.

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Shaoxi Cai Research Topics

Disease

47	Asthma (Bronchial Asthma) 02/2024 - 05/2008
29	Inflammation (Inflammations) 03/2024 - 12/2012
13	Neoplasms (Cancer) 11/2023 - 02/2007
10	Neoplasm Metastasis (Metastasis) 01/2022 - 10/2002
9	Chronic Obstructive Pulmonary Disease (COPD) 02/2024 - 01/2011
8	Pulmonary Fibrosis (Fibrosing Alveolitis) 04/2024 - 12/2017
8	Fibrosis (Cirrhosis) 03/2024 - 02/2007
6	Lung Neoplasms (Lung Cancer) 11/2023 - 10/2002
5	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 11/2023 - 11/2013
4	Metaplasia 06/2023 - 01/2016
4	Airway Remodeling 01/2023 - 06/2018
3	Lung Injury 04/2023 - 05/2015
3	Respiratory Hypersensitivity 01/2023 - 07/2015
3	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 04/2004
2	Bites and Stings (Sting) 04/2024 - 03/2024
2	Obesity 01/2024 - 09/2017
2	Carcinogenesis 11/2023 - 01/2012
2	Mitochondrial Diseases (Mitochondrial Disease) 06/2023 - 01/2017
2	Idiopathic Pulmonary Fibrosis 04/2023 - 01/2021
2	Tuberculosis (Tuberculoses) 01/2023 - 01/2016
2	Occupational Asthma 01/2021 - 06/2013
2	Breast Neoplasms (Breast Cancer) 10/2017 - 06/2013
2	Airway Obstruction (Choking) 05/2017 - 01/2011
2	Ovarian Neoplasms (Ovarian Cancer) 12/2016 - 10/2007
2	Carcinoma (Carcinomatosis) 12/2016 - 10/2002
2	Hyperplasia 11/2015 - 01/2012
2	Endotoxemia 08/2006 - 10/2005
1	Iron Overload 04/2024
1	Respiratory Tract Diseases (Respiratory Tract Disease) 02/2024

Drug/Important Bio-Agent (IBA)

15	Proteins (Proteins, Gene)FDA Link 03/2024 - 05/2008
14	Toluene 2,4-Diisocyanate (Toluene Diisocyanate)IBA 01/2024 - 06/2013
11	CateninsIBA 09/2023 - 09/2015
10	HMGB1 Protein (HMG1)IBA 01/2024 - 01/2011
8	CytokinesIBA 04/2023 - 05/2008
6	Cadherins (E-Cadherin)IBA 02/2022 - 06/2013
6	Receptor for Advanced Glycation End ProductsIBA 02/2022 - 01/2016
5	Monoclonal AntibodiesIBA 11/2023 - 01/2016
5	CollagenIBA 06/2023 - 04/2006
5	Immunoglobulin E (IgE)IBA 02/2022 - 07/2015
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2018 - 01/2012
4	Bleomycin (Blenoxane)FDA LinkGeneric 03/2024 - 01/2021
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2024 - 05/2017
4	SteroidsIBA 09/2023 - 05/2017
4	Thymic Stromal LymphopoietinIBA 03/2022 - 01/2017
4	ErbB Receptors (EGF Receptor)IBA 01/2022 - 10/2007
4	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2020 - 01/2011
3	Therapeutic UsesIBA 11/2023 - 05/2000
3	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2023 - 12/2017
3	LigandsIBA 03/2022 - 10/2007
3	GoldIBA 02/2020 - 01/2011
3	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 10/2017
3	LipopolysaccharidesIBA 09/2018 - 09/2013
3	Biomarkers (Surrogate Marker)IBA 01/2018 - 01/2011
3	Chemokine CXCL12IBA 04/2012 - 10/2007
3	CXCR4 Receptors (CXCR4 Receptor)IBA 06/2008 - 10/2007
2	tetrandrineIBA 03/2024 - 01/2021
2	N- ((2,3- dihydro- 1,4- benzodioxin- 2- yl)methyl)- 5- methoxy- 1H- indole- 3- ethanamineIBA 02/2024 - 05/2017
2	Bronchodilator Agents (Bronchodilators)IBA 02/2024 - 12/2020
2	mitoquinoneIBA 09/2023 - 06/2023
2	Human Serum Albumin FDA LinkGeneric 06/2023 - 04/2023
2	Stromal Interaction Molecule 1IBA 04/2023 - 04/2022
2	CalciumIBA 04/2023 - 04/2022
2	Dexamethasone (Maxidex)FDA LinkGeneric 04/2023 - 11/2020
2	Methacholine Chloride (Methacholine)FDA Link 01/2023 - 11/2015
2	Gefitinib (Iressa)FDA Link 01/2023 - 01/2019
2	SmokeIBA 04/2022 - 05/2015
2	Protein Isoforms (Isoforms)IBA 03/2022 - 12/2016
2	Lactate Dehydrogenase 5IBA 03/2022 - 01/2012
2	Transforming Growth Factor beta (TGF-beta)IBA 03/2022 - 02/2007
2	Advanced Glycation End ProductsIBA 01/2021 - 01/2017
2	Budesonide (Pulmicort)FDA LinkGeneric 01/2018 - 01/2016
2	Formoterol Fumarate (Oxis)FDA Link 01/2018 - 01/2016
2	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 01/2017 - 07/2015
2	Calcitriol (Calcijex)FDA LinkGeneric 01/2017 - 07/2015
2	ChemokinesIBA 01/2016 - 10/2007
2	Interleukin-4 (Interleukin 4)IBA 11/2015 - 07/2015
2	DecorinIBA 06/2008 - 02/2007
2	Epidermal Growth Factor (EGF)IBA 10/2007 - 02/2007
1	Polystyrenes (Polystyrene)IBA 04/2024
1	Glutathione (Reduced Glutathione)IBA 04/2024
1	MicroplasticsIBA 04/2024
1	Malondialdehyde (Propanedial)IBA 04/2024
1	tanespimycin (17AAG)IBA 03/2024
1	Hormones (Hormone)IBA 01/2024
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2024
1	Allopurinol (Remid)FDA LinkGeneric 01/2024
1	Xanthine OxidaseIBA 01/2024
1	purineIBA 01/2024
1	Nicotinamide MononucleotideIBA 12/2023
1	Sirtuin 3IBA 12/2023
1	Interleukin-17 (Interleukin 17)IBA 11/2023
1	AntioxidantsIBA 06/2023
1	Dasatinib (BMS 354825)FDA Link 06/2023
1	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2023
1	Ethidium (Ethidium Bromide)IBA 06/2023
1	ezrinIBA 04/2023

Therapy/Procedure

9	Therapeutics 10/2022 - 10/2002
3	Lab-On-A-Chip Devices 01/2018 - 12/2016
2	Nebulizers and Vaporizers (Inhaler) 01/2018 - 01/2016
1	Immunotherapy 11/2023